The Profiled Steel Sheet Dry Board (PSSDB) system is a composite structural system consisting of three basic components; Profiled Steel Sheet (PSS), Dry Board (DB), and connectors. Concrete as an infill material in the PSSDB system has earlier been shown able to increase the static and fire resistance performance of the system. This paper describes an experimental investigation on the effect of concrete infill on the dynamic behavior of the PSSDB system under human walking load. Two types of human walking speed have been considered; slow and normal. The effect of concrete infill on the dynamic behavior of the PSSDB system was identified by preparing of two samples; PSSDB without infill and PSSDB with concrete infill (PSSDBC). Peva45, plywood, self-drilling and self-tapping screws, and grade 30 concrete have been chosen as the PSS, DB, screws, and infill material respectively. Bruel & Kjaer portable and multi-channel PULSE analyzer type 3560D, ENDEVCO uniaxial accelerometers type 751-100, and impact hammers type 2302-10 were used to measure acceleration and displacement at the center of the area of DB. The results showed that using concrete as infill in the PSSDB system reduced the displacements of the system by 36.91% and 63.94% under slow and normal speed conditions of human walking respectively. Also, the accelerations of the PSSDB system under slow and normal speed conditions of human walking reduced by 29.85% and 39.19% respectively by using concrete as infill material. Furthermore, the speed of human walking affects on dynamic behavior of two panels.